Pharmaceutical Peptides

LL-37 (Cathelicidin)

LL-37 is the only cathelicidin-derived antimicrobial peptide found in humans. This 37-amino-acid peptide (beginning with two leucine residues, hence 'LL') is a critical component of the innate immune system, produced by neutrophils, macrophages, and epithelial cells. LL-37 exhibits broad-spectrum antimicrobial activity against bacteria, viruses, and fungi through direct membrane disruption. Beyond its antimicrobial role, LL-37 modulates immune responses including chemotaxis, inflammasome activation, and wound healing. Research interest in LL-37 has surged due to its potential applications in antibiotic-resistant infections and immune modulation. We supply LL-37 in high-purity lyophilized form for pharmaceutical research and antimicrobial development programs.