Sermorelin (GHRH 1-29) is a synthetic analog of growth hormone-releasing hormone (GHRH) consisting of the first 29 amino acids of the natural 44 amino acid sequence. FDA-approved for diagnostic use and treatment of growth hormone deficiency in children, Sermorelin stimulates the pituitary gland to produce and release growth hormone in a physiological pulsatile pattern. It is widely used in clinical research and anti-aging medicine protocols. As a B2B supplier, we provide pharmaceutical-grade Sermorelin in lyophilized form with verified purity exceeding 99% by HPLC analysis.
| Sequence | Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg |
| Molecular Formula | C149H246N44O42S |
| Molecular Weight | 3357.88 g/mol |
| Purity | ≥99% (HPLC) |
| Form | Lyophilized powder |
| Storage | -20°C, desiccated |
| CAS | 86168-78-7 |
Walker RF (2006) demonstrated in Clinical Interventions in Aging that Sermorelin acetate promotes physiological GH secretion patterns with minimal suppression of endogenous GHRH receptor sensitivity.
A pivotal study by Vittone J et al. (1997) in The Journal of Clinical Endocrinology & Metabolism confirmed Sermorelin's efficacy in restoring age-related GH decline without supraphysiological peaks.
Research published in Growth Hormone & IGF Research (2020) demonstrated that GHRH 1-29 maintains pulsatile GH release patterns, preserving hypothalamic-pituitary axis feedback regulation.
Sermorelin (GHRH 1-29) is a synthetic peptide consisting of the first 29 amino acids of human growth hormone-releasing hormone. It stimulates the pituitary gland to naturally produce and release growth hormone in a controlled, pulsatile manner.
We supply Sermorelin at ≥99% (HPLC) purity with full Certificate of Analysis including mass spectrometry confirmation, amino acid analysis, and endotoxin testing.
Minimum order quantities depend on the quantity and purity grade required. Contact our sales team for specific pricing and MOQ information for Sermorelin.
Sermorelin should be stored at -20°C in lyophilized form. After reconstitution, store at 2-8°C and use within 14 days. Protect from light and repeated freeze-thaw cycles.
Sermorelin acetate (brand name Geref) was FDA-approved for diagnostic evaluation of pituitary function and treatment of growth hormone deficiency in children. While Geref was discontinued commercially, the compound remains available for research and compounding pharmacy use.
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