Research Peptides

SS-31 (Elamipretide)

SS-31 (D-Arg-Dmt-Lys-Phe-NH2), also known by its clinical name Elamipretide, is a cell-permeable tetrapeptide that selectively targets the inner mitochondrial membrane. It binds to cardiolipin, a phospholipid essential for electron transport chain function, stabilizing mitochondrial cristae structure and improving oxidative phosphorylation efficiency. SS-31 is currently in advanced clinical trials for conditions involving mitochondrial dysfunction including primary mitochondrial myopathy (Barth syndrome), heart failure, and age-related macular degeneration. Research demonstrates that SS-31 can reverse age-related decline in mitochondrial function, making it a cornerstone compound in aging research. Available in high-purity lyophilized form for research applications.