Anamorelin is a selective, orally active ghrelin receptor (GHSR) agonist with anabolic and appetite-stimulating activity. It is being developed for the treatment of cancer-related cachexia and anorexia. Unlike growth hormone secretagogues, Anamorelin specifically targets appetite and lean body mass through the ghrelin signaling pathway.
| Sequence / Structure | Non-peptide small molecule ghrelin mimetic |
| Molecular Weight | 546.7 g/mol |
| Purity | ≥98% |
| Appearance | White crystalline powder |
| Storage | Store at room temperature, protect from moisture |
| Solubility | Soluble in DMSO and ethanol |
Temel JS, Abernethy AP, Currow DC, et al. (2016) — Anamorelin in patients with non-small-cell lung cancer and cachexia (ROMANA 1 and ROMANA 2). Lancet Oncol. DOI: 10.1016/S1470-2045(15)00558-6
Garcia JM, Polvino WJ. (2009) — Pharmacodynamic hormonal effects of anamorelin, a novel oral ghrelin mimetic and growth hormone secretagogue. Growth Horm IGF Res. DOI: 10.1016/j.ghir.2009.04.017
Currow DC, Maddocks M, Cella D, et al. (2017) — Efficacy of anamorelin, a novel non-peptide ghrelin analogue, in patients with advanced non-small cell lung cancer. J Cachexia Sarcopenia Muscle. DOI: 10.1002/jcsm.12181
Anamorelin is a selective, orally active ghrelin receptor agonist that stimulates appetite and promotes lean body mass through ghrelin pathway activation.
Anamorelin is primarily studied in cancer-related cachexia, where it has shown ability to increase lean body mass and appetite in clinical trials.
Our wholesale Anamorelin is manufactured to ≥98% purity with comprehensive analytical documentation.
Store Anamorelin at room temperature in a sealed container, protected from moisture and light.
While both are ghrelin receptor agonists, Anamorelin has a more selective receptor profile and shorter half-life, with clinical focus on cachexia rather than GH elevation.
Yes, we offer wholesale pricing with quantity-based discounts. Contact our team for custom quotations.
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