TB-500 is a synthetic version of the naturally occurring 43-amino-acid peptide Thymosin Beta-4 (Tβ4). It plays a critical role in tissue repair and regeneration by promoting cell migration, blood vessel formation (angiogenesis), and reduction of inflammation. In preclinical studies, TB-500 has demonstrated significant benefits for healing muscle tears, tendon injuries, and skin wounds. It is the second most popular recovery peptide after BPC-157 in the wholesale market. Available in pharmaceutical-grade lyophilized form for research and commercial applications.
| Molecular Formula | C212H350N56O78S |
| Molecular Weight | 4963.44 g/mol |
| Purity | ≥98% (HPLC) |
| Form | Lyophilized powder |
| Storage | -20°C |
| CAS | 77591-33-4 |
According to Goldstein et al. (2012) in Expert Opinion on Biological Therapy, Thymosin Beta-4 plays a central role in tissue repair through promotion of cell migration, angiogenesis, and survival signaling.
Research by Philp et al. (2004) in the Journal of Investigative Dermatology demonstrated that Thymosin Beta-4 accelerates dermal wound healing by promoting endothelial cell migration and angiogenesis.
A 2020 review in International Immunopharmacology confirmed TB-4's cardioprotective properties through activation of the Akt/mTOR signaling cascade.
Synthetic fragment of Thymosin Beta-4 protein for tissue regeneration, wound healing, and recovery from musculoskeletal injuries.
We supply TB-500 (Thymosin Beta-4) at ≥98% (HPLC) purity. Higher purity grades are available for pharmaceutical applications upon request.
The published wholesale price list applies to orders of 100+ total units across one or multiple SKUs. Smaller TB-500 orders are quoted separately via [email protected].
TB-500 (Thymosin Beta-4) should be stored at -20°C in a desiccated environment. Proper cold-chain shipping is maintained for all deliveries.
TB-500 is a synthetic peptide fragment corresponding to the active region of the naturally occurring Thymosin Beta-4 (Tβ4) protein. While full-length Tβ4 is a 43-amino acid protein (MW: 4,963 Da), TB-500 contains the specific actin-binding and wound-healing domain. According to Huff et al. (2001), this active region is responsible for the majority of Tβ4's biological activities.
Lyophilized TB-500 should be stored at -20°C in a desiccated environment under inert atmosphere. Per ICH Q1A stability guidelines, lyophilized TB-500 maintains ≥98% purity for 24+ months at -20°C. After reconstitution, store at 2–8°C and use within 14 days to prevent degradation.
Dr. Peptides employs orthogonal analytical methods: RP-HPLC (purity ≥99%), ESI-MS (molecular weight confirmation), amino acid analysis (sequence verification), and endotoxin testing (LAL method, <0.5 EU/mg). Each batch receives a unique lot-specific Certificate of Analysis.
TB-500 is available through the wholesale price list for orders of 100+ total units across one or multiple SKUs. Standard packaging: lyophilized powder in pharmaceutical-grade vials. Bulk packaging is quoted separately when needed; smaller orders are quoted via [email protected].
Yes, TB-500 is widely used in veterinary research, particularly in equine medicine. According to a 2018 study in Equine Veterinary Journal, Thymosin Beta-4 demonstrated significant benefits in tendon healing in equine models. Dr. Peptides provides veterinary-grade documentation upon request.
Modified fragment of human growth hormone (hGH176-191) engineered specifically for lipolysis and fat...
View Details Sports & Performance PeptidesStabilized C-terminal fragment of human growth hormone specifically targeting fat metabolism and lip...
View Details Sports & Performance PeptidesFull-length 43-amino-acid thymosin beta-4 protein for advanced tissue regeneration, angiogenesis, an...
View Details