Bradykinin is a nine-amino acid peptide formed from high-molecular-weight kininogen by the action of kallikrein. It is a potent mediator of inflammation, vasodilation, vascular permeability, and pain. Acting through B1 and B2 receptors, it plays important roles in cardiovascular regulation, inflammation, and nociception.
| Sequence / Structure | Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg |
| Molecular Weight | 1060.21 g/mol |
| Purity | >=98% |
| Appearance | White lyophilized powder |
| Storage | Store at -20C, reconstituted at 2-8C |
| Solubility | Soluble in water |
Regoli D, Barabe J. (1980) — Pharmacology of bradykinin and related kinins. Pharmacol Rev. DOI: 32(1):1-46
Marceau F, Regoli D. (2004) — Bradykinin receptor ligands: therapeutic perspectives. Nat Rev Drug Discov. DOI: 10.1038/nrd1522
Leeb-Lundberg LM, Marceau F, Muller-Esterl W, et al. (2005) — International Union of Pharmacology. XLV. Classification of the kinin receptor family. Pharmacol Rev. DOI: 10.1124/pr.57.1.7
A nonapeptide mediator of inflammation, vasodilation, and pain, formed from kininogen by kallikrein.
Acts through B1 (inducible, inflammation) and B2 (constitutive, acute effects) kinin receptors.
>=98% with full analytical documentation.
Inflammation, pain research, cardiovascular pharmacology, vascular permeability, and kinin-kallikrein studies.
Lyophilized at -20C, reconstituted at 2-8C.
Yes, wholesale quantities with volume discounts.
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