C-Peptide (Connecting Peptide) is a 31-amino acid peptide cleaved from proinsulin during the biosynthesis of insulin in pancreatic beta cells. Once considered biologically inert, C-Peptide has emerged as a bioactive molecule with distinct physiological functions including stimulation of Na+/K+-ATPase activity, enhancement of endothelial nitric oxide synthase, and improvement of microvascular blood flow. Clinically, C-Peptide levels serve as a reliable biomarker of endogenous insulin production, making it invaluable in diabetes diagnostics. Recent research explores its therapeutic potential in diabetic neuropathy, nephropathy, and other complications of type 1 diabetes.
| Sequence / Structure | EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ |
| Molecular Weight | 3,020.29 g/mol |
| Purity | ≥98% |
| Appearance | White lyophilized powder |
| Storage | Store at -20°C, protect from moisture |
| Solubility | Soluble in sterile water |
Wahren J, Ekberg K, Johansson J, et al. (2000) — Role of C-peptide in human physiology. Am J Physiol Endocrinol Metab. DOI: 10.1152/ajpendo.2000.278.5.E759
Johansson BL, Borg K, Fernqvist-Forbes E, et al. (2000) — Beneficial effects of C-peptide on incipient nephropathy and neuropathy in patients with Type 1 diabetes mellitus. Diabet Med. DOI: 10.1046/j.1464-5491.2000.00274.x
C-Peptide is a 31-amino acid peptide released during insulin biosynthesis. Once thought inert, it now shows biological activity in vascular function and is a key biomarker for insulin production.
Our wholesale C-Peptide is ≥98% purity with full analytical documentation.
C-Peptide is used in diabetes diagnostics, diabetic complication research, microvascular function studies, and metabolic biomarker assays.
Store at -20°C protected from moisture. Reconstituted solutions should be used within 7 days at 2-8°C.
Contact our sales team for wholesale pricing and MOQ information.
C-Peptide levels directly reflect endogenous insulin production, making it essential for distinguishing type 1 from type 2 diabetes and monitoring beta cell function.
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