Cagrilintide is a long-acting acylated analog of human amylin, designed for once-weekly subcutaneous administration. It activates amylin receptors to promote satiety, slow gastric emptying, and suppress glucagon secretion. Being developed in combination with semaglutide (CagriSema) for enhanced weight management.
| Sequence / Structure | Acylated amylin analog with extended half-life modification |
| Molecular Weight | ~4000 g/mol |
| Purity | >=98% |
| Appearance | White lyophilized powder |
| Storage | Store at -20C, reconstituted at 2-8C |
| Solubility | Soluble in water |
Lau DCW, Erichsen L, Francisco-Ziller N, et al. (2021) — Once-weekly cagrilintide for weight management in people with overweight and obesity. Lancet. DOI: 10.1016/S0140-6736(21)00957-8
Enebo LB, Berthelsen KK, Kankam M, et al. (2021) — Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 2.4 mg for weight management. Lancet. DOI: 10.1016/S0140-6736(21)00845-X
Hay DL, Chen S, Lutz TA, et al. (2015) — Amylin: pharmacology, physiology, and clinical potential. Pharmacol Rev. DOI: 10.1124/pr.115.010629
Cagrilintide is a long-acting amylin analog designed for weekly dosing that promotes satiety and metabolic regulation through amylin receptor activation.
CagriSema is the combination of cagrilintide and semaglutide, targeting both amylin and GLP-1 pathways for enhanced weight management.
Our wholesale Cagrilintide is >=98% pure with full certificates of analysis.
Amylin is co-secreted with insulin and promotes satiety, slows gastric emptying, and suppresses postprandial glucagon, complementing GLP-1 signaling.
Store lyophilized Cagrilintide at -20C. Reconstituted solutions at 2-8C.
Yes, we provide competitive wholesale pricing. Contact our team for quotations.
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