Calcitonin is a 32-amino acid peptide hormone produced by the parafollicular C-cells of the thyroid gland. It plays a key role in calcium and phosphorus homeostasis by inhibiting osteoclast-mediated bone resorption and increasing renal calcium excretion. Salmon calcitonin, which is 40-50 times more potent than human calcitonin, is widely used in osteoporosis research and treatment.
| Sequence / Structure | Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 |
| Molecular Weight | 3431.9 g/mol (salmon) |
| Purity | ≥98% |
| Appearance | White lyophilized powder |
| Storage | Store at -20°C, reconstituted at 2-8°C |
| Solubility | Soluble in water and dilute acetic acid |
Chesnut CH, Azria M, Silverman S, et al. (2008) — Salmon calcitonin: a review of current and future therapeutic indications. Osteoporos Int. DOI: 10.1007/s00198-007-0490-1
Copp DH, Cameron EC, Cheney BA, et al. (1962) — Evidence for calcitonin — a new hormone from the parathyroid that lowers blood calcium. Endocrinology. DOI: 10.1210/endo-70-5-638
Naot D, Cornish J. (2008) — The role of peptides and receptors of the calcitonin family in the regulation of bone metabolism. Bone. DOI: 10.1016/j.bone.2008.02.024
Calcitonin is a 32-amino acid peptide hormone produced by the thyroid gland that regulates calcium homeostasis by inhibiting bone resorption.
Salmon calcitonin is 40-50 times more potent than human calcitonin and has a longer half-life, making it the preferred form for both research and clinical applications.
Our wholesale Calcitonin is manufactured to ≥98% purity with full certificates of analysis.
Store lyophilized Calcitonin at -20°C. Reconstituted solutions should be refrigerated at 2-8°C.
Calcitonin is used in osteoporosis research, bone metabolism studies, calcium regulation, pain management, and osteoclast biology.
Yes, we provide competitive wholesale pricing with flexible minimum order quantities for Calcitonin.
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