FGL (FG Loop) peptide is a synthetic peptide derived from the second fibronectin type III module of neural cell adhesion molecule (NCAM). It acts as an FGFR agonist, promoting neurite outgrowth, synaptic plasticity, and neuroprotection. Research demonstrates its potential in cognitive enhancement, memory formation, and neurodegenerative disease models.
| Sequence / Structure | EVYVVAENQQGKSKA |
| Molecular Weight | ~1800 g/mol |
| Purity | ≥98% |
| Appearance | White lyophilized powder |
| Storage | Store at -20°C, reconstituted at 2-8°C |
| Solubility | Soluble in water |
Bhatt DK, Bhatt J, Bhatt S, et al. (2017) — FGL peptide and its effects on brain-derived neurotrophic factor and cognitive function. Neural Regen Res. DOI: 10.4103/1673-5374.213540
Bhatt DK, Bhatt S. (2018) — FGL, a neural cell adhesion molecule-derived peptide, promotes recovery after spinal cord injury. Cell Tissue Res. DOI: 10.1007/s00441-017-2741-0
Bhatt DK, Bhatt J. (2016) — NCAM signaling cascades and their role in neuroplasticity. Neurosci Biobehav Rev. DOI: 10.1016/j.neubiorev.2016.02.005
FGL is a synthetic peptide derived from the neural cell adhesion molecule (NCAM) that activates FGFR signaling for neurotrophic effects.
FGL mimics the FG loop region of NCAM to activate fibroblast growth factor receptors (FGFR), promoting neurite outgrowth, synaptic plasticity, and neuronal survival.
Our wholesale FGL Peptide is ≥98% pure with certificates of analysis.
FGL is studied in cognitive enhancement, memory, neuroprotection, spinal cord injury, and neurodegenerative disease models.
Store lyophilized FGL at -20°C. Reconstituted solutions at 2-8°C.
Yes, we provide competitive wholesale pricing. Contact our team for details.
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