Research Peptides

Ghrelin

Ghrelin is a 28-amino acid peptide hormone primarily produced by the stomach, unique for its octanoyl modification at Ser3. It is the endogenous ligand of the growth hormone secretagogue receptor (GHSR) and the only known orexigenic (appetite-stimulating) hormone. It plays critical roles in appetite regulation, energy homeostasis, GH secretion, and glucose metabolism.

Technical Specifications

Sequence / StructureGSS(octanoyl)FLSPEHQRVQQRKESKKPPAKLQPR
Molecular Weight3370.9 g/mol
Purity>=98%
AppearanceWhite lyophilized powder
StorageStore at -20C, reconstituted at 2-8C
SolubilitySoluble in water

Application Areas

  • Appetite regulation
  • Growth hormone research
  • Energy homeostasis
  • Metabolic disease studies
  • Ghrelin receptor pharmacology
  • Obesity research

Published Research on Ghrelin

Kojima M, Hosoda H, Date Y, et al. (1999) — Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature. DOI: 10.1038/45230

Muller TD, Nogueiras R, Andermann ML, et al. (2015) — Ghrelin. Mol Metab. DOI: 10.1016/j.molmet.2015.03.005

Nakazato M, Murakami N, Date Y, et al. (2001) — A role for ghrelin in the central regulation of feeding. Nature. DOI: 10.1038/35007508

Frequently Asked Questions About Ghrelin

A 28-amino acid hormone from the stomach, the only known appetite-stimulating hormone and endogenous GHSR ligand.

Its Ser3 octanoyl modification is essential for receptor binding and is unique among mammalian peptide hormones.

>=98% with full analytical certificates.

Appetite regulation, GH research, metabolism, obesity, and GHSR pharmacology.

Lyophilized at -20C, reconstituted at 2-8C.

Yes, competitive bulk pricing with volume discounts.

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