Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH), a decapeptide produced by the hypothalamus that stimulates the anterior pituitary to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It is used clinically for fertility assessment, treatment of hypogonadism, and as a diagnostic agent for pituitary function evaluation.
| Sequence / Structure | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 |
| Molecular Weight | 1182.29 g/mol |
| Purity | ≥98% |
| Appearance | White lyophilized powder |
| Storage | Store at -20°C, reconstituted at 2-8°C |
| Solubility | Soluble in water and saline |
Schally AV, Arimura A, Baba Y, et al. (1971) — Isolation and properties of the FSH and LH-releasing hormone. Biochem Biophys Res Commun. DOI: 10.1016/0006-291X(71)90726-8
Conn PM, Crowley WF Jr. (1994) — Gonadotropin-releasing hormone and its analogs. Annu Rev Med. DOI: 10.1146/annurev.med.45.1.391
Herbst KL, Anawalt BD, Amory JK, et al. (2002) — Acyline: the first study in humans of a potent, new gonadotropin-releasing hormone antagonist. J Clin Endocrinol Metab. DOI: 10.1210/jcem.87.7.8675
Gonadorelin is a synthetic version of gonadotropin-releasing hormone (GnRH), the hypothalamic decapeptide that controls reproductive hormone secretion by stimulating LH and FSH release from the pituitary.
Gonadorelin is used clinically for fertility assessment, pituitary function testing, treatment of hypothalamic amenorrhea, and evaluation of gonadotropin reserve.
Our wholesale Gonadorelin is manufactured to ≥98% purity with full analytical documentation including HPLC and mass spectrometry verification.
Lyophilized Gonadorelin should be stored at -20°C. After reconstitution with bacteriostatic water, store at 2-8°C and use within 14 days.
Gonadorelin is the natural GnRH sequence with a short half-life, while analogs like leuprolide or nafarelin have modified sequences for longer activity and different receptor kinetics.
We offer competitive wholesale pricing with flexible MOQ options. Contact our team for detailed pricing and volume discounts.
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