Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone composed of alpha and beta subunits, naturally produced by the placental trophoblast during pregnancy. HCG binds to and activates the luteinizing hormone/choriogonadotropin receptor (LHCGR), stimulating progesterone production by the corpus luteum to maintain early pregnancy. In research and clinical settings, HCG is used for ovulation induction, treatment of male hypogonadism, cryptorchidism, and as a diagnostic marker for pregnancy and certain tumors (choriocarcinoma, testicular cancer). Its structural and functional similarity to LH makes it an invaluable tool in reproductive endocrinology research.
| Sequence / Structure | Heterodimeric glycoprotein (α-subunit: 92 aa; β-subunit: 145 aa) |
| Molecular Weight | ~36,700 g/mol (heterodimer) |
| Purity | ≥98% (bioactivity >10,000 IU/mg) |
| Appearance | White to off-white lyophilized powder |
| Storage | Store at 2-8°C, protect from light |
| Solubility | Freely soluble in water and saline |
Cole LA. (2010) — Biological functions of hCG and hCG-related molecules. Reprod Biol Endocrinol. DOI: 10.1186/1477-7827-8-102
Stenman UH, Tiitinen A, Alfthan H, et al. (2006) — The classification, functions and clinical use of different isoforms of HCG. Hum Reprod Update. DOI: 10.1093/humupd/dml029
HCG (Human Chorionic Gonadotropin) is a glycoprotein hormone naturally produced during pregnancy that activates the LH receptor, essential for reproductive biology and clinical fertility research.
Our wholesale HCG is ≥98% with bioactivity >10,000 IU/mg, verified by bioassay and HPLC.
HCG is used in reproductive endocrinology, fertility research, tumor marker studies, and LH receptor pharmacology.
Store at 2-8°C protected from light. Reconstituted HCG should be used within 30 days when refrigerated.
Contact our team for MOQ and volume pricing.
We supply lyophilized HCG in research-grade vials with specified IU potency per vial.
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