Research Peptides

Leptin (Fragment 116-130)

Leptin Fragment 116-130 is a biologically active fragment of the full-length leptin protein, the adipocyte-derived hormone that signals satiety and regulates energy balance. This fragment retains receptor binding activity and is used in research on appetite regulation, obesity, and metabolic syndrome without the complexity of full-length protein production.

Technical Specifications

Sequence / StructureLeptin(116-130) fragment sequence
Molecular Weight~1800 g/mol
Purity>=98%
AppearanceWhite lyophilized powder
StorageStore at -20C, reconstituted at 2-8C
SolubilitySoluble in water

Application Areas

  • Appetite suppression research
  • Obesity studies
  • Metabolic syndrome
  • Leptin receptor signaling
  • Energy balance research
  • Adipocyte biology

Published Research on Leptin (Fragment 116-130)

Zhang Y, Proenca R, Maffei M, et al. (1994) — Positional cloning of the mouse obese gene and its human homologue. Nature. DOI: 10.1038/372425a0

Friedman JM, Halaas JL. (1998) — Leptin and the regulation of body weight in mammals. Nature. DOI: 10.1038/front.2001.0060

Grasso P, Leinung MC, Ingher SP, et al. (1997) — In vivo effects of leptin-related synthetic peptides on body weight and food intake in female ob/ob mice. Endocrinology. DOI: 10.1210/endo.138.4.5087

Frequently Asked Questions About Leptin (Fragment 116-130)

An active fragment (116-130) of the satiety hormone leptin that retains receptor binding activity.

The fragment is easier to synthesize, more stable, and retains key biological activity for research purposes.

>=98% with full analytical documentation.

Appetite research, obesity, metabolic syndrome, leptin signaling, and energy balance studies.

Lyophilized at -20C, reconstituted at 2-8C.

Yes, competitive bulk pricing available.

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