Myostatin Propeptide is the naturally occurring inhibitory domain of myostatin (GDF-8) that maintains myostatin in its latent, inactive form. When administered exogenously, it binds and neutralizes active myostatin, removing the biological brake on muscle growth. Research applications include muscle wasting, sarcopenia, and muscular dystrophy models.
| Sequence / Structure | Myostatin pro-domain peptide (latency-associated peptide) |
| Molecular Weight | ~27 kDa |
| Purity | >=95% |
| Appearance | White lyophilized powder |
| Storage | Store at -20C, reconstituted at 2-8C |
| Solubility | Soluble in water |
Lee SJ, McPherron AC. (2001) — Regulation of myostatin activity and muscle growth. Proc Natl Acad Sci USA. DOI: 10.1073/pnas.151270098
Wolfman NM, McPherron AC, Pappano WN, et al. (2003) — Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases. Proc Natl Acad Sci USA. DOI: 10.1073/pnas.2534946100
Bogdanovich S, Krag TO, Barton ER, et al. (2002) — Functional improvement of dystrophic muscle by myostatin blockade. Nature. DOI: 10.1038/nature01154
Myostatin Propeptide is the naturally occurring inhibitory domain of myostatin that keeps it in an inactive latent complex, effectively blocking myostatin signaling when administered exogenously.
The propeptide binds non-covalently to active myostatin, preventing it from interacting with its receptor (ActRIIB) and blocking downstream anti-growth signaling.
Our wholesale Myostatin Propeptide is >=95% pure with full quality documentation.
It is studied in muscle wasting, sarcopenia, muscular dystrophy, cachexia, and exercise physiology research.
Store lyophilized at -20C or -80C. Reconstituted solutions at 2-8C for short-term use.
Yes, we offer wholesale pricing with volume-based discounts. Contact us for details.
Potent cognitive-enhancing peptide derived from angiotensin IV......
View Details Research PeptidesSynthetic ACTH analog nootropic peptide for cognitive enhancement......
View Details Research PeptidesAnxiolytic peptide derived from tuftsin with nootropic properties......
View Details Research PeptidesMitochondrial-derived peptide that regulates metabolic homeostasis......
View Details