PEG-MGF (PEGylated Mechano Growth Factor) is a PEGylated form of the MGF splice variant of insulin-like growth factor 1 (IGF-1Ec). The PEG modification extends the biological half-life from minutes to hours. MGF is naturally produced in response to mechanical stress in muscle tissue, activating satellite cells and promoting muscle repair and growth.
| Sequence / Structure | PEGylated IGF-1Ec C-terminal peptide |
| Molecular Weight | ~5000 g/mol (with PEG) |
| Purity | >=98% |
| Appearance | White lyophilized powder |
| Storage | Store at -20C, reconstituted at 2-8C |
| Solubility | Soluble in water |
Goldspink G. (2005) — Mechanical signals, IGF-I gene splicing, and muscle adaptation. Physiology. DOI: 10.1152/physiol.00004.2005
Yang SY, Goldspink G. (2002) — Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation. FEBS Lett. DOI: 10.1016/S0014-5793(02)03918-9
Hill M, Goldspink G. (2003) — Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite cell activation following local tissue damage. J Physiol. DOI: 10.1113/jphysiol.2002.035832
PEG-MGF is a PEGylated form of Mechano Growth Factor, a splice variant of IGF-1 involved in muscle repair and satellite cell activation.
PEGylation extends the biological half-life of MGF from minutes to several hours, enabling sustained signaling.
>=98% pure with full certificates of analysis.
Muscle growth, satellite cell activation, tissue repair, exercise physiology, and IGF-1 signaling.
Lyophilized at -20C, reconstituted at 2-8C.
Yes, competitive bulk pricing with volume discounts.
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