HGH Fragment 176-191 is a stabilized analog of the growth hormone-releasing factor (GRF) that represents the fat-reducing portion of the human growth hormone molecule. This peptide fragment (amino acids 176-191 of the GH polypeptide) has been demonstrated in research to stimulate lipolysis (fat breakdown) up to 12.5 times more effectively than standard hGH, while simultaneously inhibiting lipogenesis (new fat formation). Importantly, Fragment 176-191 does not compete with hGH for receptor binding and does not induce hyperglycemia or affect insulin sensitivity. It is one of the most popular peptides in the weight management and sports nutrition wholesale market.
| Molecular Weight | 1817.12 g/mol |
| Purity | ≥98% (HPLC) |
| Form | Lyophilized powder |
| Storage | -20°C |
| CAS | 221231-10-3 |
According to comprehensive reviews in the Journal of Peptide Science, synthetic therapeutic peptides represent one of the fastest-growing segments of the pharmaceutical industry.
Research published in Trends in Pharmacological Sciences (2023) highlights the importance of peptide purity exceeding 99% for reproducible preclinical research outcomes.
Stabilized C-terminal fragment of human growth hormone specifically targeting fat metabolism and lipolysis without systemic growth effects.
We supply Fragment 176-191 at ≥98% (HPLC) purity. Higher purity grades are available for pharmaceutical applications upon request.
Minimum order quantities for wholesale Fragment 176-191 depend on the quantity and purity grade required. Contact our sales team for specific pricing and MOQ information.
Fragment 176-191 should be stored at -20°C in a desiccated environment. Proper cold-chain shipping is maintained for all deliveries.
Every batch includes a comprehensive Certificate of Analysis with HPLC purity data (≥99%), mass spectrometry confirmation, amino acid analysis, endotoxin testing (<0.5 EU/mg), and residual solvent analysis per ICH Q3C guidelines.
In-stock peptides are dispatched within 48 hours of order confirmation. International delivery takes 5–7 business days via temperature-controlled shipping. Express 2–3 day options available. Our on-time delivery rate is 99.2%.
Yes. Dr. Peptides provides Drug Master File (DMF) documentation, Certificates of Origin, MSDS/SDS in multiple languages, and stability data packages compliant with ICH guidelines for regulatory submissions.
Dr. Peptides offers a 100% money-back quality guarantee. If any product fails to meet the purity specifications stated on its Certificate of Analysis, we provide a full replacement or refund within 48 hours of claim receipt.
All shipments use pharmaceutical-grade insulated packaging with qualified gel packs maintaining 2–8°C for up to 96 hours. Each package includes a temperature data logger for verification upon receipt, per WHO guidelines for temperature-sensitive pharmaceuticals.
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