Substance P is an 11-amino acid neuropeptide from the tachykinin family that acts primarily through the neurokinin 1 (NK1) receptor. It plays crucial roles in pain transmission, neurogenic inflammation, mood regulation, and immune cell activation. It is one of the most extensively studied neuropeptides in neuroscience and immunology.
| Sequence / Structure | Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 |
| Molecular Weight | 1347.63 g/mol |
| Purity | >=98% |
| Appearance | White lyophilized powder |
| Storage | Store at -20C, reconstituted at 2-8C |
| Solubility | Soluble in water |
Steinhoff MS, von Mentzer B, Geppetti P, et al. (2014) — Tachykinins and their receptors: contributions to physiological control and the mechanisms of disease. Physiol Rev. DOI: 10.1152/physrev.00031.2013
Munoz M, Covenas R. (2014) — Involvement of substance P and the NK-1 receptor in human pathology. Amino Acids. DOI: 10.1007/s00726-014-1736-9
Mashaghi A, Marmalidou A, Tehrani M, et al. (2016) — Neuropeptide substance P and the immune response. Cell Mol Life Sci. DOI: 10.1007/s00018-016-2293-z
Substance P is an 11-amino acid neuropeptide from the tachykinin family, primarily acting through NK1 receptors in pain and inflammation.
Substance P mediates pain transmission, neurogenic inflammation, mood regulation, immune cell activation, and emesis.
>=98% pure with full certificates of analysis.
Pain research, neuroinflammation, NK1 receptor pharmacology, mood disorders, and immune modulation.
Lyophilized at -20C, reconstituted at 2-8C.
Yes, competitive bulk pricing available.
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