Acetyl Hexapeptide-8, commercially known as Argireline, is a synthetic hexapeptide that mimics the N-terminal end of SNAP-25, a protein essential for neurotransmitter release at neuromuscular junctions. By competing with SNAP-25 in the SNARE complex, Argireline reduces the release of neurotransmitters that cause facial muscle contraction, thereby diminishing expression lines and wrinkles. Often marketed as 'Botox in a jar,' clinical studies demonstrate up to 30% wrinkle depth reduction after 30 days of topical application. Argireline is one of the most commercially successful cosmetic peptides globally. We supply it in pharmaceutical-grade bulk quantities for cosmetic formulation houses and contract manufacturers.
| Sequence | Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2 |
| Molecular Weight | 888.96 g/mol |
| Purity | ≥95% (HPLC) |
| Form | Powder / Solution |
| Storage | 2-8°C |
| CAS | 616204-22-9 |
| INCI | Acetyl Hexapeptide-8 |
According to comprehensive reviews in the Journal of Peptide Science, synthetic therapeutic peptides represent one of the fastest-growing segments of the pharmaceutical industry.
Research published in Trends in Pharmacological Sciences (2023) highlights the importance of peptide purity exceeding 99% for reproducible preclinical research outcomes.
Neurocosmetic hexapeptide for expression line reduction  the 'topical alternative to botulinum toxin' for anti-wrinkle formulations.
We supply Acetyl Hexapeptide-8 (Argireline) at ≥95% (HPLC) purity. Higher purity grades are available for pharmaceutical applications upon request.
Minimum order quantities for wholesale Acetyl Hexapeptide-8 (Argireline) depend on the quantity and purity grade required. Contact our sales team for specific pricing and MOQ information.
Acetyl Hexapeptide-8 (Argireline) should be stored at 2-8°C in a desiccated environment. Proper cold-chain shipping is maintained for all deliveries.
Every batch includes a comprehensive Certificate of Analysis with HPLC purity data (≥99%), mass spectrometry confirmation, amino acid analysis, endotoxin testing (<0.5 EU/mg), and residual solvent analysis per ICH Q3C guidelines.
In-stock peptides are dispatched within 48 hours of order confirmation. International delivery takes 5–7 business days via temperature-controlled shipping. Express 2–3 day options available. Our on-time delivery rate is 99.2%.
Yes. Dr. Peptides provides Drug Master File (DMF) documentation, Certificates of Origin, MSDS/SDS in multiple languages, and stability data packages compliant with ICH guidelines for regulatory submissions.
Dr. Peptides offers a 100% money-back quality guarantee. If any product fails to meet the purity specifications stated on its Certificate of Analysis, we provide a full replacement or refund within 48 hours of claim receipt.
All shipments use pharmaceutical-grade insulated packaging with qualified gel packs maintaining 2–8°C for up to 96 hours. Each package includes a temperature data logger for verification upon receipt, per WHO guidelines for temperature-sensitive pharmaceuticals.
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