Cosmetic Peptides

Palmitoyl Pentapeptide-4 (Matrixyl)

Palmitoyl Pentapeptide-4, commercially known as Matrixyl, is one of the most extensively studied and validated cosmetic peptide ingredients in the skincare industry. It consists of a five-amino-acid sequence (Lys-Thr-Thr-Lys-Ser) conjugated with palmitic acid to enhance skin penetration. Clinical studies have demonstrated that Matrixyl stimulates collagen I, III, and IV synthesis, as well as fibronectin and hyaluronic acid production, leading to measurable reduction in wrinkle depth and improvement in skin texture. Multiple double-blind clinical trials confirm its anti-aging efficacy. We supply Matrixyl in bulk powder and solution forms for cosmetic manufacturers and private-label skincare brands.

Technical Specifications

SequencePal-Lys-Thr-Thr-Lys-Ser
Molecular Weight802.05 g/mol
Purity≥95% (HPLC)
FormPowder / Solution
Storage2-8°C
CAS214047-00-4
INCIPalmitoyl Pentapeptide-4

Application Areas

  • Preclinical research protocols
  • In vitro and in vivo studies
  • Pharmaceutical development
  • Academic research applications
  • Biotech R&D programs

Published Research & Quality Assurance

According to comprehensive reviews in the Journal of Peptide Science, synthetic therapeutic peptides represent one of the fastest-growing segments of the pharmaceutical industry.

Research published in Trends in Pharmacological Sciences (2023) highlights the importance of peptide purity exceeding 99% for reproducible preclinical research outcomes.

Frequently Asked Questions About Palmitoyl Pentapeptide-4 (Matrixyl)

Clinically proven cosmetic peptide for collagen stimulation, wrinkle reduction, and skin rejuvenation in anti-aging formulations.

We supply Palmitoyl Pentapeptide-4 (Matrixyl) at ≥95% (HPLC) purity. Higher purity grades are available for pharmaceutical applications upon request.

Minimum order quantities for wholesale Palmitoyl Pentapeptide-4 (Matrixyl) depend on the quantity and purity grade required. Contact our sales team for specific pricing and MOQ information.

Palmitoyl Pentapeptide-4 (Matrixyl) should be stored at 2-8°C in a desiccated environment. Proper cold-chain shipping is maintained for all deliveries.

Every batch includes a comprehensive Certificate of Analysis with HPLC purity data (≥99%), mass spectrometry confirmation, amino acid analysis, endotoxin testing (<0.5 EU/mg), and residual solvent analysis per ICH Q3C guidelines.

In-stock peptides are dispatched within 48 hours of order confirmation. International delivery takes 5–7 business days via temperature-controlled shipping. Express 2–3 day options available. Our on-time delivery rate is 99.2%.

Yes. Dr. Peptides provides Drug Master File (DMF) documentation, Certificates of Origin, MSDS/SDS in multiple languages, and stability data packages compliant with ICH guidelines for regulatory submissions.

Dr. Peptides offers a 100% money-back quality guarantee. If any product fails to meet the purity specifications stated on its Certificate of Analysis, we provide a full replacement or refund within 48 hours of claim receipt.

All shipments use pharmaceutical-grade insulated packaging with qualified gel packs maintaining 2–8°C for up to 96 hours. Each package includes a temperature data logger for verification upon receipt, per WHO guidelines for temperature-sensitive pharmaceuticals.

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